Wales produced a stirring second half to crush England's Grand Slam dream with a record-breaking 12th consecutive Test win.
England had led 10-3 at the interval after 20-year-old Tom Curry's first international try garlanded a brutal defensive display.
But Wales came barrelling back and took the lead with 13 minutes to go when second row Cory Hill smashed over after a relentless series of drives.
And with replacement Dan Biggar taking control, Josh Adams sealed it at the death as he claimed his fly-half's cross-field kick to send the Principality Stadium into ear-splitting ecstasy.
If Wales can beat Scotland in Edinburgh in two weeks' time only Ireland in Cardiff on the final day of the championship will stand between them and a first Grand Slam since 2012.
But this will go down as another masterclass from their coach Warren Gatland, as England were unable to get close to their form of the opening two rounds.
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